Suzana BV Mello,1 Elaine R Tavares,2 Adriana Bulgarelli,2 Eloisa Bonfá,1 Raul C Maranhão2,31Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; 2Lipid Metabolism Laboratory, the Heart Institute (INCOR) of the Medical School Hospital, São Paulo, Brazil;

ATP-binding cassette (ABC) transporters are highly expressed by brain endothelial cells that form the blood-brain barrier (BBB).These efflux SHARK LIVER OIL pumps play an important role in maintaining brain homeostasis as they actively hinder the entry of unwanted blood-derived compounds into the central nervous system (CNS).Consequently, their hig

BACKGROUND: Sequence analysis is a set of tools increasingly used in demography and other social sciences to analyse longitudinal categorical data.Typically, single (e.g., education trajectories) or multiple parallel temporal processes (e.g., work and family) are analysed by using crisp clustering algorithms that reduce complexity by partitioning c

Summary: The presence of personally identifiable information (PII) in natural language portions of electronic health records (EHRs) constrains their broad reuse.Despite continuous improvements in automated detection of PII, residual identifiers require manual validation and correction.Here, we describe an automated de-identification system that emp

Abstract Background Glioma is the most commonly diagnosed malignant and aggressive brain cancer in adults.Traditional researches mainly explored the expression profile of glioma at cell-population level, but ignored the heterogeneity and interactions of among glioma cells.Methods Here, we firstly analyzed the single-cell RNA-seq (scRNA-seq) data of